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The routine, medically unnecessary use of antibiotics to
promote the enhanced growth of livestock is making disease-causing
bacteria more resistant to the drugs, which diminishes their power
to treat life-threatening diseases in humans.
Click here to go to
the printable petition (Word document).
For centuries, infections like pneumonia and tuberculosis caused
by bacteria were a major cause of disease and death. The discovery
of antibiotics has proven critical in greatly reducing infectious
diseases, and protecting public health relies heavily on the use
of these drugs. But repeated exposure to antibiotics enables
resistant strains of bacteria to evolve. Some bacteria
are naturally resistant, so they survive treatment and multiply.
When antibiotics are given again, the resistant bacteria remain.
As the resistant strain within the bacterial population increases
over time, the drugs become less effective. The more antibiotics
we use, the more likely it is that bacteria will become resistant.
The Institute of Medicine, part of the National Academy of Sciences,
estimated that the annual cost of treating antibiotic-resistant
infections in the U.S. might be as high as $30 billion. (National
Institute of Allergy and Infectious Diseases)
The increased use of antibiotics in animal production
has gone hand-in-hand with the development of industrial-style livestock
operations. Thousands of animals are crammed into
the unhygienic, crowded quarters of a typical factory operation,
and antibiotics are dispensed constantly through the animals' feed.
Twenty-five million pounds of antibiotics are fed to American
livestock annually. This is about 70% of the total amount
of antibiotics produced in the U.S. each year and eight times more
than the amount used as human medicine. (Union of Concerned Scientists,
2001) Scientists do not understand how or why the drugs promote
growth. Many of the same antibiotics -- six of the 17 classes of
antibiotics -- used to promote growth in animals are also used to
treat diseases in humans. (The New York Times, 1999)
Evidence is increasingly showing that resistance to
treatment, caused by the overuse of antibiotics, threatens public
health.
Drug-resistant infections, some of which are fatal, have been
increasing in the U.S. population. Many scientists attribute the
problem to the misuse of antibiotics in humans and animals. (The
New York Times, 1999) Although it is not the only source of the
problem, the use of antibiotics to promote livestock growth
is a major contributor to antibiotic resistance.
According to the Center for Disease Control, more than
one-third of the salmonella poisoning cases in 1997 were found to
be resistant to five antibiotics. Drug resistance in campylobacter
bacteria, the most commonly known cause of bacterial food-borne
illness in the United States, increased from zero in 1991 to 14
percent in 1998. (The New York Times, 1999)
A Harvard University study showed that antibiotic-resistant genes
found in bacteria infecting humans were identical to some of the
same bacteria infecting animals. (O'Brien et.al., 1982) Scientists
at the Center for Disease Control linked an outbreak of
antibiotic-resistant salmonella in humans to beef cattle that had
been fed sub therapeutic doses of chlortetracycline for growth promotion.
(Holmberg, et.al., 1984)
A more recent study by the University of California-Berkeley cited
the use of antibiotics in livestock as a possible cause for the
emergence of drug resistant strains of E.coli that cause female
urinary tract infections. Twenty-two percent of the strains collected
at the Berkeley site were resistant to a common antibiotic used
to treat bladder infections. (Yang, 2001)
Staph bacteria, which cause skin, blood, heart
valve, and bone infections that can lead to septic shock and death,
are becoming increasingly resistant to methicillin,
the chief antibiotic used to treat such infections. From 1975 to
1991, the incidence of methicillin-resistant staph bacteria in U.S.
hospitals has increased from 2.4 percent to 29 percent. Staph infections
are also becoming increasingly resistant to the last line of defense,
vancomycin. (Panlilio, 1992)
The European Union, on the recommendation of the World Health
Organization, has banned the use of antibiotics to promote the growth
of livestock animals when those drugs are also used to treat people.
The Center for Disease Control has agreed with this position, but
the U.S. government has failed to reduce the threat that ineffective
antibiotics pose to human health. (Lieberman, et.al., 1999)
In Pennsylvania, the Sierra Club is calling for a ban on the non-therapeutic
use of antibiotics in animal feed. We have launched a petition drive
to convince Governor Ed Rendell to take the lead in banning the
unnecessary use of antibiotics in animal factory farms in Pennsylvania.
Please sign our petition, and circulate it to your friends and neighbors.
When it is completed, please send it to us at: Sierra Club, P.O.
Box 663, Harrisburg, PA 17108
For more information about the Sierra Club's opposition to factory
livestock production, contact the Pennsylvania Chapter office at
pennsylvania.chapter@sierraclub.org
or call (717) 232-0101.
Click here to return to issues page.
Click here to go to
the printable petition (Word document).
________________________________________
Sources:
Holmberg, S.D., Osterholm, M.T., Senger, K.A., and Cohen, M.L.,
"Drug-resistant Salmonella from animals fed antimicrobials."
New England Journal of Medicine 1984; 311:617-622.
Lieberman, Patricia, et.al., "Protecting the Crown Jewels of
Medicine. A Strategic Plan to Preserve the Effectiveness of Antibiotics,"
Center for Science in the Public Interest, 1999.
National Institute of Allergy and Infectious Diseses, "Antimicrobial
Resistance Fact Sheet," http://www.niaid.nih.gov/factsheets/antimicro.htm.
March, 1999.
The New York Times, "A Move to Limit Antibiotic Use In Animal
Feed. Fewer Hardy Bacteria in People is U.S. Goal." March 8,
1999.
O'Brien, T.F., Hopkins, J.D., Gilleece, E.S., Mederios, A.A., Kent,
R.L., Blackburn, .O., Holmes, M.B., Reardon, J.P., Vregeront, J.M.,
Schell, W.L., Christenson, E., Bissett, M.L., and Morse, E.V., Molecular
epidemiology of antibiotic resistance in salmonella from animals
and human beings in the United States, New England Journal of Medicine
1982; 307: 1-6.
Panlilio, A.L., "Methicillin-resistant Staphylococcus aureus
in U.S. Hospitals, 1975-1991, Infection Control Epidemiology,"
1992; 1
Union of Concerned Scientists, "70 Percent of All Antibiotics
Given to Healthy Livestock," http://www.ucsusa.org/releases/01-08-01.html.
January 8, 2001.
Yang, Sarah, "New multi-drug resistant strain of E. coli emerges
in three distinct regions, new UC Berkeley study finds," http://www.berkeley.edu/news/media/releases/2001/10/03_virus.htm.
October 3, 2001.
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